Always turn rods clockwise. Turning anti-clockwise unscrews the joints, and a lost rod head in a drain becomes a permanent blockage that needs retrieval or excavation.
Rods push a hole through an obstruction rather than removing it, so flow may return while the deposit remains. That is why jetting is the professional default.
For a gully or a short run they are a reasonable DIY tool. For anything beyond that, they are the wrong equipment.